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The three major indexes all fell by more than 1%, with nearly 4,200 stocks, and the index weakened sharply. The Shanghai Composite Index fell by more than 1%, the Shenzhen Component Index fell by 1.24%, and the Growth Enterprise Market Index fell by 1.45%. Securities, real estate and photovoltaics were among the top losers, with nearly 4,200 stocks falling in Shanghai, Shenzhen and Beijing.Inter-bank cash bonds are strong as a whole, and national debt and CDB active bonds are down by 3-5bp. The 5-year treasury bonds and CDB active bonds went down by about 5bp, and "24 Treasury bonds with interest 20" reported 1.42%, which was a record low compared with yield to maturity, a Chinese bond in the same period, and "24 CDB 08" reported 1.515% in the same period, a record low since January 26th, 2006. The 10-year "24 interest-bearing treasury bonds 11" initially declined, and now it remains below 1.8%.Shanghai Securities: The pharmaceutical and bio-industry is expected to further repair its performance and valuation. The Shanghai Securities Research Report pointed out that with the support of policies and the adjustment of the internal structure of the industry, the pharmaceutical and bio-industry is expected to further repair its performance and valuation. It is suggested to pay attention to five directions: 1) Innovative drugs (with strong national policy support, the payment terminal is expected to further improve and go to sea to occupy the global market); 2)CXO (the negative impact of the biosafety bill event has been eliminated, and the demand for orders in the superimposed interest rate reduction cycle has increased, which is expected to usher in a double repair of performance and valuation); 3) Imitation and innovation (centralized procurement is expected to clear up, increase innovation, and traditional pharmaceutical companies will usher in new opportunities); 4) Traditional Chinese Medicine (the national policy supports the innovation of traditional Chinese medicine, and its performance is expected to maintain a good growth rate); 5) Medical devices (equipment updating, high-consumption innovation, low-consumption going to sea, etc.). Individual stocks can be concerned about: Baekje Shenzhou, Wuxi PharmaTech, China Resources Sanjiu and so on.

The total output of automobiles in Shenzhen is expected to exceed 2.8 million vehicles this year. Last year, Shenzhen ranked among the "First City of New Energy Vehicles in China" with an output of 1.733 million vehicles. This year, the total output is expected to exceed 2.8 million vehicles, and it is expected to win the title of "First City of Automobile in China" again. (released by Shenzhen)Japan's Topix index fell to 1%.Foreign media: Trump "strongly opposes" Ukraine's use of American-made missiles to attack Russia's hinterland, and at the same time says that he will not give up Ukraine. According to Reuters's report, US President-elect Trump criticized Ukraine's use of American-made missiles to attack targets in Russia on the 12th local time, arguing that this has aggravated the escalation of the war between Russia and Ukraine. However, he also mentioned that he would not give up Ukraine. When talking about the Russian-Ukrainian conflict, Trump said in an interview, "What happened is crazy. This is crazy. I strongly object to launching missiles hundreds of miles into Russia. Why are we doing this? This will only escalate this war and make the situation worse. " According to the report, Trump hopes to end this "war" that lasted for nearly three years as soon as possible, but he is more cautious about revealing specific details. When asked if Kiev would cut its military and humanitarian aid to Ukraine if it did not agree to the peace agreement, Trump responded, "I think I have a very good plan to help Ukraine, but when I started to disclose this plan, it would almost become a worthless plan." In addition, when asked if he would give up Ukraine, Trump replied, "I hope to reach an agreement, and the only way to reach an agreement is not to give up." (World Wide Web)

Pengyue Automobile Development Co., Ltd., a subsidiary of Tucki, was forced to enforce 680,000 yuan. According to the risk information of Tianyan, recently, Guangzhou Pengyue Automobile Development Co., Ltd. and Hunan Chunqiu Engineering Co., Ltd. added a piece of information about the person to be executed, with an execution target of more than 684,000 yuan, involving construction contract disputes. The enforcement court is Tianhe District People's Court of Guangzhou. Guangzhou Pengyue Automobile Development Co., Ltd. was established in August 2021, with the legal representative of Zhao Dawu and the registered capital of 1.88 billion RMB. Its business scope includes auto parts retail, tire sales, investment activities with its own funds, electric vehicle charging infrastructure operation, industrial design service and motor vehicle charging sales, etc. It is wholly owned by Guangzhou Xpeng Motors Technology Co., Ltd.The Hang Seng Index and Hang Seng Technology Index both fell more than 1%.The United States ITC officially launched a 337 investigation on injection molding machines, their components and downstream products. According to China Trade Relief Information Network, on December 12, the United States International Trade Commission (ITC) voted to launch a 337 investigation (investigation code: 337-TA-1427) on specific injection molding machines, their components and downstream products.